Archive for August, 2007

Freeman Dyson Biology on NYRB.com: Woese for the wear

Freeman Dyson writes in the Jul 19 2007 NYRB, “our Biotech Future”; and discusses biology which is ‘bigger than physics’ now in a number of ways. Well, the first premise is true enough. But, as he notes, it is accepted wisdom. Let’s get into which is not accepted and which is not wise, ok? He then starts to discuss genetic engineering, which he indicates is moving now from centrally controlled development to disbursed open system development, and he suspects that the real advances will be on their way now as the same everyday folks who managed, over many eras, to create new types of dog and plant breeds, will be able to work their democratic magic directly on genes soon, moving to the lab what once took place in the hot house or the kennel.

Dyson worked in the company of John von Neumann in the distant past -  after all, John von left our midst in the 1950s -  and he saddles the long-departed Neumann  with blinkers [‘Blinkered vision”] – with the “vision of computers as large centralized facilities.” [Does von Neumann’s late innings’ interest in cellular automata count for anything?] You might think that this infers that Freeman in the 1950s could see what was coming in computers and biology, or at least that von Neumann didn’t see it. Doesn’t this seem a bit unfair? Is a score being settled?

JvN failed to see says Freeman that small and domesticated would be the evolution rather than “big and centralized.” That’s part one.

From there he goes on to talk about Carl Woese and “A new Biology for a New Century” in which he posits the brewing cross breeder wave with the imagined primordial soup of Woese, before the bacteria struck off on its own, began to specialize, before the first species, when all the bits used to intermingle. Hold on to your hats folks, because those funky days are back again. Maybe.

The bit of usefulness here in an largely charming piece is that Freeman explores the notion that reductionist science has reached a deadend, or, to be more faithful, has reached a point where it needs a serious adjunct arm dedicated to holistic system technology. Some of the parts are worth more than the hole.

The piece ends with a bit of a brickbat cast at the Green folks who don’t endorse Green Technology. Freeman Dyson says ‘if the technology is developed carefully and deployed with sensitivity to human feelings, it is like to be accepted by most of the people who will be affected by it.”  But let us face it, the whole antiFrankenfoods movement makes perfect sense as Monsanto and its buddies just darkly at night without much public forum started bringing the genetic engineered produce online. What where has changed? The Monsanto fate should be studied closely, and maybe some one will learn how to behave better. In the mean time, the question is: When the hell was there evey a time when a technology was carefully deployed with sensitivity to human feelings?

Meanwhile one important Freeman question goes begging. How long will it take us to grow plants with silicon leaves?

But dont take my word, read it yourself:
http://www.nybooks.com/articles/20370
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Add comment August 27, 2007

IBM Press room – 2007-08-15 DREAM Organizers Announce Cellular Network Pred

The National Center for Biomedical Computing at Columbia University, in collaboration with the IBM (NYSE: IBM) Computational Biology Center at IBM T.J. Watson Labs, today announced a call for participation at its yearly workshop for the assessment of methods for reverse engineering of biological circuits.

The Dialogue for Reverse Engineering As

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Add comment August 22, 2007

MIT creates 3-D images of living cell

A new imaging technique developed at MIT has allowed scientists to create the first 3D images of a living cell, using a method similar to the X-ray CT scans doctors use to see inside the body.

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Add comment August 22, 2007


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